А.V. Batukhtin, I.V. Shilovа, N.I. Suslov, S.G. Aksinenko

Vaccinium myrtillus L. (Ericaceae) extract obtained by treating of the shredded sprouts plants by 70 % ethanol in a water bath with reflux cooleir for 1,5 hours at a temperature of 80-85 º C and the ratio of raw material-extractant is 1:7. Fraction obtained by extraction with an aqueous solution of a consistent extract a number of solvents with increasing polarity: chloroform, ethyl acetate, butanol-1. In experimental test the extract was administered at a dose of 200 mg/kg, the factions - in equivalent doses: chloroform - 16 mg/kg, of ethyl acetate - 17 mg/kg, butanol - 34 mg/kg and water balance - 133 mg/kg. Introduction of the extract and its fractions, helped to preserve the performance of the exploratory behavior of mice in open field after the hypoxic exposure at or above the values of intact controls. The most pronounced effect render ethyl acetate, chloroform fractions and the whole extract, exceeding the activity of piracetam. The extract and fractions of Vaccinium myrtillus L eliminate amnesia of passive avoidance caused by hypoxic injury. When using the extract and its chloroform fraction enhance of reflex reproduction obtained recorded higher than in the group treated with piracetam.