I.E. Ivanova, I.N. Sergeeva, A.V. Skalny

There were studied the prevalence of nephrological morbidity (total and admission rate), peculiarities of pyelonephritis, the frequency of congenital malformations and minor renal abnormalities in children living in different ecological-biogeochemical territories of Chuvashia, and the elemental composition of hair in patients with and without kidney malformations. A significant increase in nephrological morbidity in children along 7 years (2002-2008.) was revealed, especially among teenagers aged 15-17. It was shown that the overall renal morbidity, prevalence of congenital kidney malformations, clinical and laboratory peculiarities of pyelonephritis are different in children, living in heterogeneous areas. It was established that a characteristic feature of children with developmental kidney malformations is elevated hair level of heavy metals (lead, cadmium, tin, nickel) and aluminum on the background of a high incidence of a zinc deficiency. There were studied the prevalence of nephrological morbidity (total and admission rate), peculiarities of pyelonephritis, the frequency of congenital malformations and minor renal abnormalities in children living in different ecological-biogeochemical territories of Chuvashia, and the elemental composition of hair in patients with and without kidney malformations.