Radiotekhnika
Publishing house Radiotekhnika

"Publishing house Radiotekhnika":
scientific and technical literature.
Books and journals of publishing houses: IPRZHR, RS-PRESS, SCIENCE-PRESS


Тел.: +7 (495) 625-9241

 

Journal Biomedical Radioelectronics №2 - 2019 year.

DOI 10.18127/j15604136-201902-01

In order to obtain large volumes of heating during radiofrequency ablation of tumors, a thermal imaging study of temperature fields created in a bioobject simulator by multielectrode systems was carried out. In the experiments, a domestic four-channel installation for ablation of METATOM-3 tumors was used, allowing to connect from 1 to 12 electrodes with thermocouples to the generator and to control their temperature, setting in advance one or another profile of temperature change over time on the control unit. For the first time, potato tubers were used as a simulator that performs the indication of a thermal field in radio frequency heating. The essence of thermal fixation was that when heated in the range from 58 to 62, potato starch changes its structure from coarse-grained to fine-grained. The resulting sponge draws water from the surrounding volume, and the volumetric pattern of heating has clearly limited boundaries that persist for a long time. The picture of the temperature field obtained on flat potato slices using a thermal imager made it possible to judge not only the lateral temperature distribution, but also the longitudinal distribution. Research results showed that, depending on the location of bipolar electrodes, two configurations of the thermal field can be created in the simulator: in the form of a cylindrical tube with a wall width of 10 to 20 mm and a solid circular cylinder whose height is equal to the length of the working part of the applied electrodes. The latter configuration allows the introduction of electrodes into the ablastic zone to destroy tumors with a diameter greater than 70 mm in a time not exceeding 15 minutes. The results obtained in this work indicate the technical possibility of a substantial increase in the volume of tissue being destroyed during RFA by increasing the number of electrodes and placing the electrodes in the tumor volume closer to the periphery, including the ablastics zone. As a result, it becomes possible to heat tumors from their periphery without contact of the electrodes with the tumor with a significant reduction in the risk of distant metastasis. The increase in the number of heat sources allows not only to reduce the load on the electrodes, but also to reduce the time of the procedure. Clinical testing carried out in a number of oncological centers confirmed the results of experimental studies obtained on bioobject simulators.

5-14

DOI 10.18127/j15604136-201902-02

E.S. Petrova – Junior Research Scientist, Head of the Laboratory of Experimental Physiology in IBMT, Research Center of Balneology and Rehabilitation of Federal Medical Biological Agency (Sochi, Russia)
E-mail: pirogovka04@yandex.ru
V.Z. Agrba – Dr.Sc.(Med.), Head of the Laboratory of biology and immunology of cells of FSBSI «RIMP», Sochi
E-mail: agrba_vz@mail.ru
G.G. Karal-Оgly – Ph.D. (Biol.), Senior Research Scientist, Laboratory of biology and immunology of cells, Research Institute of Medical Primatology (Sochi, Russia)
E-mail: karal_5@mail.ru
A.A. Lubyako – D.Sc. (Biol.), Professor, Head of IBMT Department, Research Center of Balneology and Rehabilitation of Federal Medical Biological Agency (Sochi, Russia)
E-mail: lubyako@bk.ru

15-29

DOI 10.18127/j15604136-201902-03

R.V. Isakov – Ph.D. (Eng.), Associate Professor, Department of Biomedical and Electronic Means and Technologies, Vladimir State University n.a. A.G. and N.G. Stoletov
E-mail: Isakov-RV@mail.ru
I.I. Alexeeva – Undergraduate, Department of Biomedical and Electronic Means and Technologies, Vladimir State University n.a. A.G. and N.G. Stoletov
E-mail: aly33xa@mail.ru

30-37

DOI 10.18127/j15604136-201902-04

N.V. Anisimov – Dr.Sc. (Phys.-Math.), Senior Research Scientist, Laboratory of a Magnetic Tomography and Spectroscopy, Faculty of Fundamental Medicine, Lomonosov Moscow State University
E-mail: anisimovnv@mail.ru
A.G. Agafonnikova – Student, Department of Photonics and Physics of Microwaves, Faculty of Physical, Lomonosov Moscow State University
E-mail; agafon4ik96@yandex.ru
A.V. Kosenkov – Student, Department of Biophysics, Faculty of Physical, the Lomonosov Moscow State University
E-mail: koss1741@yandex.ru
Yu.A. Pirogov – Dr.Sc. (Phys.-Math.), Professor, Faculty of Physics, M.V. Lomonosov Moscow State University National Research Nuclear University MEPhI, Engineering Physics Biomedical Institute
E-mail: yupi937@gmail.com

38-46

DOI 10.18127/j15604136-201902-05

A.B. Burlakov – Dr. Sc. (Biol.), Professor, Leading Research Scientist, Department of Ichthyology, Faculty of Biology, Lomonosov Moscow State University
E-mail: burlakovao@mail.ru
A.F. Gadzaov – Ph.D. (Eng.), Associate Professor, Department of Applied Mathematics, Moscow Technological University
E-mail: gadzaov_alex@yandex.ru
A.S. Machikhin – Ph.D. (Phys.-Math.), Leading Research Scientist, Scientific and Technological Center of Unique Instrumentation of RAS
Е-mail: machikhin@ntcup.ru
D.D. Khokhlov – Junior Research Scientist, Scientific and Technological Center of Unique Instrumentation of RAS
Е-mail: khokhlov.dd@ntcup.ru

47-55

DOI 10.18127/j15604136-201902-06

N.A. Temuryants – Dr.Sc. (Biol.) (1945–2018)
K.N. Tumanyants – Ph.D. (Biol.), Director, V.I. Vernadsky Crimean Federal University (Simpheropol)
E-mail: tumanyantsk@gmail.com
A.S. Kostyuk – Ph.D. (Biol.), Assistant, Kiev National University n.a. Taras Shevchenko
E-mail: timur328@gmail.com
N.S. Yarmolyuk – Ph.D. (Biol.), Associate Professor, V.I. Vernadsky Crimean Federal University (Simpheropol)
E-mail: timur328@gmail.com

56-62

DOI 10.18127/j15604136-201902-07

S.N. Novikov – Ph. D. (Eng.), Leader Research Scientist, Institute nano- and the microsystem equipment, National Research University of Electronic Technology (MIET) (Moscow, Zelenograd)
E-mail: aviary@mail.ru
A.I. Ermolaeva – Ph. D. (Eng.), Associate Professor, Institute nano- and the microsystem equipment, National Research University of Electronic Technology (MIET) (Moscow, Zelenograd)
V.A. Zhigalov – Ph. D. (Eng.), Engineer, Institute nano- and the microsystem equipment, National Research University of Electronic Technology (MIET) (Moscow, Zelenograd)
E-mail: zhigalov@gmail.com
N.E. Korobova – Dr. Sc. (Chem.), Professor, Leader Research Scientist, Institute nano- and the microsystem equipment National Research University of Electronic Technology (MIET) (Moscow, Zelenograd)
E-mail: korobova3@mail.ru

63-68

© Издательство «РАДИОТЕХНИКА», 2004-2017            Тел.: (495) 625-9241                   Designed by [SWAP]Studio