Radiotekhnika
Publishing house Radiotekhnika

"Publishing house Radiotekhnika":
scientific and technical literature.
Books and journals of publishing houses: IPRZHR, RS-PRESS, SCIENCE-PRESS


Тел.: +7 (495) 625-9241

 

Molecular structure and water-degradation properties of polylactide and composite polylactide-based coatings deposited from the active gas phase

DOI 10.18127/j22250980-201901-04

Keywords:

A.A. Rogachev – Dr.Sc. (Eng.), Professor, Belarusian state university of transport (Gomel’, Republic Belarus)
Е -mail: rogachev78@mail.ru


Typical features of the molecular structure, orientation of macromolecules of polylactide (PL) coating, their changes when silver na-noparticles are introduced into the volume were examinated by FTIR, FTIR-ATR spectroscopy in polarized light and atomic force mi-croscopy. The PL coatings deposited from the electron-beam dispersion products have a mainly amorphous structure with the orientation of the PL macromolecules in the interface up to 100 nm thick parallel to the substrate surface. During the deposition of silver-containing PL coatings, a higher content of silver nanoparticles was established when dispersing a mixture of polymer and silver nitrate under conditions of its assisting with laser radiation with  = 266 nm and heating the coating to a temperature above 200 °C. Coatings are characterized by a high rate of hydrolytic degradation, leading to the formation of a porous structure. A high tendency of coatings to hydrolytic degradation and swelling were established, which allows to recommend such layers to create multicomponent systems with controlled release of drug components from the polymer matrix.

References:
  1. Gritsenko K.P., Krasovsky A.M. Thin film deposition of polymers by vacuum degradation // Chem. Rev. 2003. V. 103. № 9. P. 3607–3649.
  2. Rogachev A.A. Fiziko-himiya polimernyh pokrytij, osazhdaemyh iz aktivnoj gazovoj fazy. M.: Nauchnyj mir. 2014. 287 s.
  3. YArmolenko M.A. i dr. Mikro- i nanokompozicionnye polimernye pokrytiya, osazhdaemye iz aktivnoj gazovoj fazy / Pod red. A.V. Rogacheva. M.: Radiotekhnika. 2016. 424 s.
  4. Fredenberg S., Wahlgren M., Reslow M., Axelsson A. The mechanisms of drug release in poly (lactic-co-glycolic acid)-based drugdelivery systems – A review // International Journal of Pharmaceutics. 2011. V. 415. P. 34–52.
  5. Tapal'skij D.V., Bojcova N.YU., Osipov V.A., Rogachev A.A., YArmolenko M.A., Rogachev A.V., Marchenko L.A., Butovskaya G.V., Krul' L.P. Novoe antibakterial'noe pokrytie na osnove smesi poliuretana i poli-L-laktida // Doklady NAN Belarusi. 2013. T. 57. № 4. S. 89–95.
  6. Krul' L.P., Butovskaya G.V., SHahno O.V., Rogachev A.A., Rogachev A.V., Tapal'skij D.V., Skakovskij E.D., Tychinskaya L.YU. Mekhanizm formirovaniya polilaktidnyh pokrytij iz aktivnoj gazovoj fazy // Doklady nacional'noj akademii nauk Belarusi. 2016. T. 60 № 3. S. 72–80.
  7. Rogachev A.A., Yarmolenko M.A., Rogachou A.V., Tapalski D.V., Xiaoheng Liuc, Gorbachev D.L. Morphology and structure of antibacterial nanocomposite organic–polymer and metal–polymer coatings deposited from active gas phase // RSC Advances. 2013. V. 3. № 28. P. 11226–11233
  8. Rogachev A.A., Tamulevičius S., Rogachev A.V., Yarmolenko M.A., Prosycevas I. The structure and molecular orientation of polytetrafluoroethylene coatings deposited from active gas phase // Applied Surface Science. 2009. V. 255. № 15. P. 6851–6856.
  9. Bellami L. Infrakrasnye spektry slozhnyh molekul. M.: Mir. 1963. 592 s.
  10. Krul' L.P., Butovskaya G.V., SHahno O.V., Rogachev A.A., Rogachev A.V., Tapal'skij D.V., Skakovskij E.D., Tychinskaya L.YU. Mekhanizm formirovaniya polilaktidnyh pokrytij iz aktivnoj gazovoj fazy // Doklady Nacional'noj akademii nauk Belarusi. 2016. T. 60. № 3. S. 72–78.
  11. Marchenko L.A. i dr. Struktura i svojstva tonkih plenok poli-L-laktida // Sviridovskie chteniya: Sb. st. / Belorus. gos. un-t; redkol.: O.A. Ivashkevich (pred.) i dr. Minsk. 2014. Vyp. 10. S. 247–261.
  12. Lamellar Orientation and Crystallization Dynamics of Poly (L-Lactic Acid) Thin Films Investigated by In-Situ Reflection Absorption Infrared Spectroscopy Ningjing Wu, Meichun Ding, Chenwei Li, Yuan Yuan, and Jianming Zhang / J. Phys. Chem. B. 2011. V. 115. P. 11548–11553.
  13. Trofimov V.I. Priroda centrov zarodysheobrazovaniya pri vakuumnoj kondensacii // FTT. 1975. T. 17, № 2. C. 1279–1282.
  14. Jones M.R., Osberg K.D., Macfarlane R., Langille M.R., Mirkin C.A. Templated Techniques for the Synthesis and Assembly of Plasmonic Nanostructures // Chem. Rev. 2011. V. 111. P. 3736–3827.
  15. Krul' L.P., Butovskaya G.V., Rogachev A. A., Tapal'skij D.V. Struktura i svojstva poli-L-laktida v tonkoplenochnom sostoyanii // Himiya novyh materialov i biologicheski aktivnyh veshchestv / Pod obshch. red. D.V. Sviridova. Minsk: BGU. 2016. S. 268–286. 343 c.
  16. Sharp J.S.? Jones R. A. L. Swelling-induced morphology in ultrathin supported films of poly (d, l− lactide) // Phys. Rev. E. 2002. V. 66. № 1. P. 011801.
June 24, 2020
May 29, 2020

© Издательство «РАДИОТЕХНИКА», 2004-2017            Тел.: (495) 625-9241                   Designed by [SWAP]Studio