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Clinical signs of different types of pigmented skin lesions for early diagnostics for the purpose of early detection of precancerous skin changes

DOI 10.18127/j15604136-201805-03


Elena Rimskaya - Bauman Moscow State Technical University, Moscow 105005, Russia

Irina Apollonova - Bauman Moscow State Technical University, Moscow 105005, Russia

Alexsandr Nikolaev - Bauman Moscow State Technical University, Moscow 105005, Russia

Konstantin Kudrin - Sechenov First Moscow State Medical University, Moscow 119991, Russia

Igor Reshetov - Sechenov First Moscow State Medical University, Moscow 119991, Russia

Nikita Chernomyrdin - Bauman Moscow State Technical University, Moscow 105005, Russia

Kirill Zaytsev - Bauman Moscow State Technical University, Moscow 105005, Russia,  Prokhorov General Physics Institute of RAS, Moscow 119991, Russia


Among other lesions of the skin, a special attention is paid to the melanoma because of its extreme aggressiveness. Melanoma remains the leading cause of death in patients with oncodermatology [1]. A steady increase of morbidity and mortality form melanoma is observed all over the world. Since efficiency of the melanoma treatment strongly depends on its early diagnosis, the development of novel highly-efficient methods for the early detection of dysplastic skin nevi and melanomas in situ remains a challenging problem of modern medicine, applied physics and engineering sciences. Visual examination of the skin and dermatoscopy remain the most widely applied methods for non-invasive diagnosis of dysplastic skin nevi and melanomas in situ [2]. Other techniques, such as fluorescence imaging [3,4], ultrasound diagnosis [5,6], confocal laser microscopy [7-9], thermometry [10-12], provide additional information and seem to be prospective instruments for clarifying diagnosis. An accuracy of visual dermatoscopy strongly depends on the experience of the doctor and a number of other factors that influence the process of assessing the severity of the disease. Numerous errors could occur during the visual diagnosis, among which there are errors of a subjective nature, as well as errors associated with the use of the particular diagnostic technique. A promising way to improve the effectiveness of early noninvasive diagnosis of melanoma is to use the correctly-selected early diagnosis method for various types of skin pigmented lesions.

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