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Hardware-software complex for the study of saccades in Huntington's disease

Keywords:

L.A. Chigaleychik - Ph.D. (Med.), Senior Research Scientist, Scientific Center of Neurology (Moscow)
E-mail: chigalei4ick.lar@yandex.ru
V.V Poleshchuk - Ph.D. (Med.), Senior Research Scientist, Scientific Center of Neurology (Moscow)
E-mail: pol82@yandex.ru


The aim of this study was to investigate saccadic parameters in 12 patients with early stages of Huntington's disease. The control group consisted of 15 healthy subjects, the corresponding age and sex. Neurophysiological monitoring was carried out by EOG in the complex «Gaze». Saccades duration were significantly different from the norm in all patients, eye movements were abnormal  asymmetrical and jumping. The results found a violation of the saccades duration and disorders of eye trajectory in HD, more pronounced in the coordination test.

References:
  1. Fedotova E.Ju., Chechetkin A.O., Abramycheva N.Ju., Chigalejchik L.A., Bazijan B.H., Ponomareva T.A., Alekseeva N.S., Fedin P.A., Kravchenko M.A., Varakin Ju.Ja., Iva-nova-Smolenskaja I.A., Illarioshkin S.N. Identifikacija lic v latentnoj stadii bolezni Parkinsona (issle-dovanie PARKINLAR): pervye rezul'taty i optimi-zacija algoritma // Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. T. 115. №6. S. 411.
  2. Patent № 2146494 (RF). Sposob diagnostiki dviga-tel'nyh funkcij cheloveka i ustrojstvo dlja ego realizacii. / B.H. Bazijan.
  3. Chigalejchik L.A., Damjanovich E.V., Teslenko E.L., Pole-shhuk V.V., Bazijan B.H. Primenenie novogo appparatno-programmnogo kompleksa dlja issledovanija semiotiki sakkad pri bolezni Parkinsona // Zhurnal Nejrokomp'-jutery: razrabotka, primenenie. 2016. № 6. S 4749.
June 24, 2020
May 29, 2020

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