Radiotekhnika
Publishing house Radiotekhnika

"Publishing house Radiotekhnika":
scientific and technical literature.
Books and journals of publishing houses: IPRZHR, RS-PRESS, SCIENCE-PRESS


Тел.: +7 (495) 625-9241

 

The study of correlations between the content of chemical elements in hair, liver, kidney, muscle outbred white rats

Keywords:

A.A. Skalny – Post-graduate Student, Federal State Institution of Science «Institute of Toxicology of the Federal Medical-Biological Agency», St. Petersburg. E-mail: scalny@rambler.ru M.V. Melikhova – Leading Research Scientist, Federal State Institution of Science «Institute of Toxicology of the Federal Medical-Biological Agency», St. Petersburg. E-mail: melihovamarina@inbox.ru E.Yu. Bonitenko – Dr.Sc. (Med.), Director, Federal State Institution of Science «Institute of Toxicology of the Federal Medical-Biological Agency», St. Petersburg. E-mail: eu_bonitenko@toxicology.ru A.V. Skalny – Dr.Sc. (Med.), Professor, Leading Research Scientist, Federal State Institution of Science «Institute of Toxicology of the Federal Medical-Biological Agency», St. Petersburg; Director, Federal State Educational Government-financed Institution of Higher Professional Education «Orenburg State University», Orenburg. E-mail: skalny3@microelements.ru M.G. Skalnaya – Dr.Sc. (Med.), Professor, Federal State Educational Government-financed Institution of Higher Professional Education «Orenburg State University», Orenburg; Senior Research Scientist, State Scientific Institution «All-Russian Research Institute of Beef Cattle Breeding», Orenburg. E-mail: skalnaya@yandex.ru S.A. Miroshnikov – Dr.Sc. (Biol.), Professor, Director, Federal State Educational Government-financed Institution of Higher Professional Education «Orenburg State University», Orenburg; Director, State Scientific Institution «All-Russian Research Institute of Beef Cattle Breeding», Orenburg. E-mail: vniims.or@mail.ru


Correlations between the content of chemical elements in the tissues outbred white rats-males was studied. The analysis of hair, liver, kidneys, myocardium and hip (thigh) muscle of the content of such macro and trace elements as Ca, Mg, Fe, Zn, Cu, Mn and Se was carried out by ICP-MS. The direct correlation between the content of Ca, Zn, Cu in liver, Ca and Zn in kidneys and Ca in myocardial muscle and fur of healthy experimental animals was found. From the results of the correlation analysis of the obtained data suggest that analysis of hair on the content of cal-cium, zinc, copper is an informative method to assess the status of these elements in a healthy organism of rats and reflects their active participation in metabolic processes. It is shown that the analysis of wool that accurately reflects the content of some chemical elements in the internal organs and muscles, which can be seen as the rationale of this test as a method of control of the content of chemical elements in organs and tissues.
References:

 

  1. Revich B.A. KHimicheskie ehlementy v volosakh cheloveka kak indikator vozdejjstvija zagrjaznenijj proizvodstvennojj i okruzhajushhejj sredy // Gigiena i sanitarija. 1990. № 3. S. 55-59.
  2. Skalnyjj A.V.,Grabeklis A.R., Demidov V.A., Skalnaja M.G., Berezkina E.S. Svjaz ehlementnogo statusa naselenija Centralnogo federalnogo okruga s zabolevaemostju. CH. 2. EHssencialnye i uslovno ehssencialnye khimicheskie ehlementy // Mikroehlementy v medicine. 2012. T. 13. Vyp. 2. S. 1-7.
  3. Lugovaja E.A., Maksimov A.L. EHlementnyjj profil organizma zhitelejj Severo-Vostoka Rossii // Voprosy biologicheskojj, medicinskojj farmacevticheskojj khimii. 2012. № 6. S. 17-21.
  4. Miroshnikov S.A., Notova S.V., Kvan O.V. Izuchenie vzaimosvjazi nakoplenija tjazhelykh metallov v volosakh i tkani shhitovidnojj zhelezy u lic, prozhivajushhikh v uslovijakh ehkologicheski neblagoprijatnogo regiona // Voprosy biologicheskojj, medicinskojj i farmacevticheskojj khimii. 2012. № 6. S. 30-34.
  5. Momcilovic B., Prejac J., Visnjevic V., Skalnaya M.G., Mimica N., Drmic S., Skalny A.V. Hair iodine content in assesing the human iodine status // Thyroid. 2014. V. 17. № 6. P. 1421-1429.
  6. Skalnyjj A.V., Slavin F.I., Semjonov A.S. KHronicheskaja alkogolnaja intoksikacija i mikroehlementnyjj sostav volos // Sudebno-medicinskaja ehkspertiza. 1990. № 1. S. 42-43.
  7. Pereira R., Pereira M.L., Ribeiro R., Goncalves F. Tissues and hair residues and histopathology in wild rats (Rattus rattus L.) and Algerian mice (Mus spretus Lataste) from an abandoned mine area (Southeast Portugal) // Environmental Pollution. 2006. V. 139. P. 561-575.
  8. Lesage F.-X., Deschamps F., and Millart H. Lead levels in fur of rats treated with inorganic lead measured by inductively coupled argon plasma mass spectrometry // Interdiscip Toxicol. 2010. V. 3. № 4. P. 118–121.
  9. Zamana S.P. Opredelenie khimicheskogo ehlementnogo sostava volosjanogo pokrova u krupnogo rogatogo skota // Selskokhozjajjstvennaja biologija. 2006. № 4. S. 121-125.
  10. Evropejjskaja Konvencija o zashhite pozvonochnykh zhivotnykh, ispolzuemykh dlja ehksperimentov ili v inykh nauchnykh celjakh. Strasburg. 1986. 18 s.
  11. MUK 4.1.1482-03, MUK 4.1.1483-03. Opredelenie khimicheskikh ehlementov v biologicheskikh sredakh i preparatakh metodami atomno-ehmissionnojj spektrometrii s induktivno svjazannojj plazmojj i mass-spektrometrii s induktivno svjazannojj plazmojj. Federalnyjj centr gossanehpidnadzora Minzdrava Rossii. 2003. 56 s.
  12. Zajjko O.A. Svjaz interernykh pokazatelejj svinejj porody SM-1 s akkumuljaciejj khimicheskikh ehlementov v organakh i shhetine // Sb. materialov VII mezhregion. konf. molodykh uchenykh i specialistov agrar. vuzov Sib. feder. okruga. «Innovacionnyjj potencial molodykh uchenykh v razvitii agropromyshlennogo kompleksa Sibiri» Novosibirsk. 2009. S. 168-170.

 

June 24, 2020
May 29, 2020

© Издательство «РАДИОТЕХНИКА», 2004-2017            Тел.: (495) 625-9241                   Designed by [SWAP]Studio