A.V. Kobelev, S.I. Shchukin, E. Matevossian, A. Schneider, K.F. Stock
The aim of this study is an experimental research on laboratory animals to determine the mechanisms of liver’s electrical impedance, also known as rheogepatogram. Electrical impedance was recorded directly from the liver, which abdomen animal is under general anesthesia was opened. Signals were recorded at four different cardiorespiratory states.
In case of the breath-hold the pulse flow oscillations give the main contribution to the electrical impedance changes. In case of breathing the impedance signals are due to pulse fluctuations in blood flow and also reflect changes in respiratory venous liver. Consideration of the breathing in the development of liver’s control systems based on impedance techniques will differentiate the contribution of arterial and venous blood flow, which gives additional diagnostic information about the liver’s state.